NEDP in the news
Genesis Drug Discovery & Development (GD3), a member of Genesis Global Group, acquires JSS Medical Research to expand its clinical services portfolio.
Post May, 2023
Hamilton, New Jersey – May 10, 2023. Genesis Drug Discovery and Development (GD3), Contract Research Organization (CRO) arm and member of Genesis Global Group (GGG), announced today that it has acquired JSS Medical Research. With corporate headquarters in Montreal, Canada, and regional offices in Bogotá, Columbia, Faridabad, India, and Warsaw, Poland, JSS Medical Research provides pre- and post-approval clinical development services to support pharmaceutical, biotechnology, nutraceutical and medical device companies worldwide.
This clinical service portfolio addition will enable the GD3 member companies to expand their full-service drug research and discovery services. JSS Medical Research's skilled team of world-class scientists will work synergistically and augment GD3's existing platform of services in clinical trial support, including clinical trial management, protocol development, biostatistics, clinical data management, clinical study monitoring, biostatistics and medical writing, medical monitoring, safety reporting, and project management for the development and approval of pharmaceutical, nutraceutical and medical device products.
"The single most important factor that drove our decision to accept Genesis Global Group's acquisition offer for JSS Medical Research was that, similarly to JSS, GD3 has its origin rooted in science, and it is an organization committed to scientific excellence. Both GD3 and JSS have science as their core foundation. The merger of the two companies creates an organization that will deliver state-of-the-art scientific support and services to our combined and growing list of pharmaceutical, biotechnology and medical device clients. As one entity, we will be able to conveniently support our clients throughout the drug development life cycle, including discovery, epidemiological, pre-clinical, clinical, post-marketing, health economics and real-world evidence. For the management and employees of JSS, this is an exciting next phase in the evolution of our company that will accelerate our access to new markets both geographically and in our service offerings. We are all delighted to be part of GD3 and are committed to creating a unique health research organization that will set new standards in the industry," stated Dr. John S. Sampalis, Ph.D., F.A.C.E., F.A.H.A., Chief Executive Officer and Chief Scientific Officer of JSS Medical Research.
"The merging of GD3 with JSS enables GD3 to move further along the pathway of being able to offer a fully vertically integrated development process to its valued clients. Continuity of a trusted relationship established in good service and good science is a win-win for all," noted Louise Bussieres, President and CFO of JSS Medical Research.
"This acquisition demonstrates our ongoing commitment to evolve our services to meet the needs of our industry partners," says Eli Mordechai, Ph.D., CEO of GGG. "By adding JSS Medical Research's sector expertise, we continue to differentiate our capabilities and significantly enhance our clinical services portfolio worldwide. We are confident that together we will create a more powerful platform to support the approval of life-saving therapeutics."
"This newest addition represents the next step in our global scale-up as we continue to expand into a global market," said Ben Bandaru, Ph.D., Director of Corporate Development for GGG. "The acquisition of JSS Medical Research creates an even more integrated and powerful global network for our industry partners."
FOS Advisors, New York, served as an advisor to JSS for the transaction with GGG.
About JSS Medical Research JSS Medical Research is a full-service clinical research organization (CRO) with strong academic affiliations offering a wide range of services internationally. One of their distinguishing attributes is their methodological knowledge and expertise in the design and execution of clinical studies. These include all phases of development, such as Phase I, II and III, and post-approval studies. The breadth of their experience enables our clients to collaborate with the same partner throughout the product lifecycle.
About Genesis Global Group Genesis Global Group (GGG) is a consortium of vertically integrated companies with a mission of improving patient care by cross-linking their expertise, dedication, and vision in drug discovery, personalized and tailored clinical diagnostics, integrated state-of-the-art, women's health care services, and through the development, manufacturing, and distribution of unique biotechnology-based products.
About Genesis Drug Discovery & Development Genesis Drug Discovery & Development (GD3) is a fully integrated CRO providing services to support drug discovery programs of our clients from target discovery through IND filing and managing Phase I-IIII clinical trials. The GD3 worldwide portfolio includes services for HTS and assay development, synthetic organic and medicinal chemistry, DMPK/in-vivo pharmacology and safety pharmacology, toxicology, and clinical trial services for the regulatory approval of novel drug and medical device products.To find out more, please visit www.genesisbiotechgroup.com. Contact: Anthony Rohr, Chief Operating Officer firstname.lastname@example.org 844-272-8234
Genesis Axis Acquires Organochem to Grow the Preclinical Chemistry Services Portfolio.
Posted January 2023
Hamilton, New Jersey – January 10, 2023. Genesis Axis that manages the international Contract Research Organization (CRO) arm of Genesis Drug Discovery and Development™ (GD3 ), announced today that it has acquired Organochem. Located in Budapest, Hungary, Organochem provides a broad spectrum of smart chemistry products and services to support the design of new drugs and other bioactive products for pharmaceutical and biotechnology clients worldwide. In the United States, GD3 is managed by Genesis Global Group (GGG).
This portfolio addition will enable the GD3 member companies to expand their full-service drug research and discovery offerings by augmenting their chemistry capabilities and accelerating the screening, selection, and the advancement of their industry partner's drug candidates. Organochem's skilled team of world-class chemists will work synergistically with GD3 's existing platform of chemistry services around uHTS, computational chemistry, medicinal chemistry and structural biology.
"Joining the Genesis Axis and GD3 is a great opportunity for Organochem to join forces with a fully integrated CRO. This merger will allow us to provide our unique chemistry services to the drug discovery programs of major pharmaceutical companies in new parts of the world. Thanks to the professional knowledge and commitment of our employees, we expect significant development and growth of our highly specialized business lines as a member of Genesis Axis. This acquisition proves that Genesis Axis recognizes and highly values the results achieved by Organochem," says Zoltán Dalicsek, Ph.D., CEO of Organochem.
"We have an ongoing commitment to evolve our services for the worldwide pharmaceutical and biotechnology communities," says Dr. Eli Mordechai, CEO of Genesis Axis and GGG. "By adding Organochem's sector expertise and global reach, we continue to differentiate our capabilities and significantly enhance our catalog of chemistry services to better serve our industry partners."
"This newest addition to the GD3 portfolio adds complementary services allowing us to expand into new markets and continue to scale up globally," said Ben Bandaru, Ph.D., Director of Corporate Development for GGG. "The acquisition of Organochem aligns with GD3's mission for continued expansion into the global market and for creating an even more integrated and powerful global network for our industry partners."
"Organochem’s scientists will join forces with our highly skilled synthetic and medicinal chemists in GD3 to advance our partners’ programs,” says Dr. Joyce Huang, Ph.D., CSO Chemistry of GD3
Genesis Biotechnology Group Acquires BioBlocks to Grow the Preclinical Chemistry Services Portfolio of Genesis Drug Discovery & Development (GD3)
Posted October 2021
Genesis Biotechnology Group® (GBG) and Contract Research Organization (CRO) arm Genesis Drug Discovery & Development™ (GD3) announced today that it has acquired BioBlocks. Founded in San Diego in 2002, BioBlocks provides medicinal chemistry drug discovery services and products to clients worldwide from initial lead discovery through the identification of development candidates.
This chemistry service portfolio addition will enable the GD3 member companies to expand their full-service drug research and discovery services to augment medicinal chemistry capabilities and accelerate screening, selection, and the advancement of industry partner's drug candidates. With offices and laboratories in San Diego, California, and Budapest, Hungary, BioBlock's skilled team of world-class chemists, with over 100 years of combined pharma and CRO experience, will work synergistically with GD3's existing platform of chemistry services around uHTS, computational chemistry, and structural biology.
"We welcome the opportunity to become a member of the Genesis family of companies after 20 years of building an organization with strengths in medicinal chemistry expertise and collaborative drug discovery," says Dr. Peter Pallai, CEO of BioBlocks. “By combining the complementary CRO capabilities of GD3 members and BioBlocks, we are creating a most comprehensive coverage of the drug discovery spectrum that will provide exceptional services to our pharma/biotech partners."
"We constantly adapt our services to meet the needs of our industry partners," says Dr. Eli Mordechai, CEO of GBG. "I believe that adding BioBlocks' sector expertise and global reach is another way to differentiate our capabilities and significantly enhance our portfolio around medical chemistry to better serve our industry partners."
"While we continue to add complementary services to expand into new markets, we are also adding scale to increase market share with our existing services," said Ben Bandaru, Ph.D., Director of Corporate Development for GBG. "The acquisition of BioBlocks is our first foray into establishing a base in the epicenter of European Biotech and Pharma, which seemed like our logical next step."
Genesis Drug Discovery & Development Appoints Laura Sailor Veteran CRO Business Development Leader as Director of Business Development
Posted September 2021
Genesis Drug Discovery & Development (GD3), the contract research organization (CRO) arm of Genesis Biotechnology Group® (GBG), has announced the appointment of Laura Sailor as its new Director of Business Development. In this role she will inspire and drive a highly specialized business development team to initiate, develop and maintain productive relationships at all levels within pharmaceutical and CRO organizations. Laura will leverage GD3’s portfolio of integrated, full-service solutions, discovery workflows and subject matter expertise to achieve accelerated growth in competitive market segments.
“GD3 is in a fascinating phase of growth, and the timing is perfect to make a difference in patient’s lives,” said Laura Sailor about this new opportunity.
Laura brings more than 25 years of experience in the Pharma and Contract Research industries to the GD3 team. She previously held key positions in business development at Icaria Life Sciences, PTM Biolabs, HarkerBIO, WuXi App Tech, Aptuit, Emerald Bio (Beryllium Discovery), and Crown Bioscience.
"I am delighted to welcome Laura to the GD3 leadership team and am excited to work alongside this industry veteran. I look forward to drawing from her expertise, deep market knowledge, and proven ability to build high functioning teams to innovate business development strategies across all GD3 member companies," said Dr. Eli Mordechai, CEO of Genesis Biotechnology Group.
Genesis Drug Discovery & Development Appoints Anthony Rohr as Chief Operating Officer
Posted September 2021
Genesis Drug Discovery & Development (GD3), the contract research organization (CRO) arm of Genesis Biotechnology Group® (GBG), has announced the appointment of Anthony Rohr, current Chief Executive Officer of PharmOptima, as its new Chief Operating Officer. In this capacity, as an expansion of Anthony's current role, he will provide operational leadership, oversight, and coordination across all GD3 member companies. Anthony brings a wealth of experience in a senior leadership capacity from his previous role at MPI Research, Inc. He is an experienced strategist with deep industry knowledge and an understanding of building CRO business while leveraging operational scale across a dispersed footprint. He is a strong leader with a proven track record of developing diverse and high-performing teams.
"I am delighted to continue my professional journey with the Genesis Biotechnology Group," said Anthony Rohr. “Along with my fellow leadership team, I am excited to help build upon our successes. We are going to persist in our efforts to capitalize on our gifted researchers' talents, our commitment to quality and communication, and our commitment to growth through organic development and acquisition. This commitment to ascendancy will continue our trajectory toward becoming the preeminent CRO in the preclinical industry and beyond."
Anthony began his career with GBG as the Business Development Manager for PharmOptima in 2018. In 2020, he transitioned into his previous role of Chief Executive Officer of PharmOptima. As the CEO of PharmOptima, Anthony provided leadership, oversight, and coordination for developing and managing new preclinical drug discovery platforms within PharmOptima. Prior to joining GBG, he held a position with MPI Research, Inc., as Senior Director of Operations. Anthony was also the owner of Knowledgeable and Focused Consulting, where he provided science and business development consulting services to Biotech, CRO, and Pharma.
Anthony has distinguished himself with 20 years of experience in the pharmaceutical, biotechnology, and CRO industries. "Anthony has been instrumental in building business development and operations functions at PharmOptima. I am thrilled to have Anthony expand his role and look forward to drawing from his expertise in developing new business strategies and leading our high-performing teams across all GD3 member companies," said Dr. Eli Mordechai, CEO of Genesis Biotechnology Group.
Genesis Drug Discovery and Development acquires Integrated Analytical Solutions to add "off the shelf" PK profiling capabilities to its portfolio
Posted March 2021
Genesis Biotechnology Group® (GBG) and its Contract Research Organization (CRO) arm Genesis Drug Discovery & Development™ (GD3) announced today that it has acquired the Berkeley-based CRO Integrated Analytical Solutions (IAS). Founded in 2004 and located in the San Francisco bay area, IAS is a GxP-compliant CRO providing bioanalytical, drug metabolism, and analytical chemistry services to clients worldwide.
“This is our second acquisition in the space of two months as we further expand our presence in the San Francisco bay area, which we see as a market with tremendous growth potential for drug discovery services” said Eli Mordechai, Ph.D., Chief Executive Officer (CEO) of GBG. “Adding IAS’s GxP compliant bioanalytical platform to GD3’s existing portfolio would allow us to further broaden our services around PK profiling and GLP toxicology while being in close proximity to our pharma and biotech partners on the west coast.”
“While we continue to add complementary services to expand into new markets, we are also adding scale to increase market share with our existing services” said Ben Bandaru, Ph.D., Director of Corporate Development for GBG. “Acquisition of IAS provides scale for our bioanalytical capabilities in a GLP setting.”
“The team at IAS is honored and excited to join forces with the GD3 family of CROs. We strongly believe that our membership in the GD3 portfolio will position IAS to better serve current clients while also broadening our reach to develop new customers” said Jonah Michaelian, IAS’s Managing Director. “The acquisition by GD3 will enable IAS to realize the full potential of the analytical and regulatory infrastructure it has built over the past sixteen years and to establish itself as a center for bioanalytical excellence.”
Genesis Drug Discovery and Development expands its presence in the clinical space by acquiring STATKING Clinical Services
Posted January 2021
Genesis Biotechnology Group® (GBG) and its Contract Research Organization (CRO) arm Genesis Drug Discovery & Development™ (GD3) announced today that it has acquired the Cincinnati-based CRO STATKING Clinical Services. Established in 1989, STATKING provides clinical trial services, including clinical trial management, protocol development, biostatistics, clinical data management, clinical study monitoring, medical writing, medical monitoring, safety reporting, and project management for the regulatory approval of novel drug and medical device products.
“We are very pleased to have STATKING join GBG, and this acquisition demonstrates our commitment to making GD3 a fully integrated concept to commercialization CRO,” said Eli Mordechai, Ph.D., Chief Executive Officer (CEO) of GBG. “STATKING’s acquisition strengthens our services and strategic presence throughout the life cycle of the drug development process. STATKING has achieved significant milestones in its 30 years of service, and I look forward to an exciting future together.”
“The way pharma companies work with CROs is changing. CROs are taking more of a strategic planning role, in addition to execution, in the drug discovery and development process. This model of engagement results in sponsors and CROs becoming end-to-end partners, and M&A is helping CRO’s extend their service portfolio to partner with their customers in providing greater efficiency in service and delivery across R&D continuum. The acquisition of STATKING would bring GD3 one more step closer to becoming a full service CRO” said Ben Bandaru, Ph.D., Director of Corporate Development for GBG.
STATKING and GD3 share a common vision that delivering better therapies to patients faster requires an integration of drug discovery and clinical trial services” said Rod Lashley. The addition of STATKING’s clinical services to GD3’s integrated, early-late stage drug discovery solutions will create a unique platform for clients to work with one scientific partner to enhance the speed and efficiency with which they can advance their therapies into the clinics.
Genesis Biotechnology Group announces second year of CRO relationship with Yale University
Posted December 2020
Genesis Biotechnology Group® (GBG) and its CRO arm Genesis Drug Discovery & Development™ (GD3) announced today that it has expanded its relationship with Yale University to continue to offer GD3’s integrated portfolio of preclinical services to the awardees of the Blavatnik Fund for Innovation. Initiated in 2018, this is a part of GD3’s efforts to offer early drug discovery-based services to Yale’s researchers, allowing their breakthrough research to get to the market as new drugs and treatments.
“We are delighted to partner with Yale University for a second year to accelerate the transition of fundamental biomedical discoveries into commercialization opportunities,” said Eli Mordechai, PhD, Chief Executive Officer (CEO) of GBG. “Our partnership with Yale will continue building our ongoing strong and mutually beneficial relationship with the Blavatnik Fund and Office of Cooperative Research at Yale.”
“We are deeply privileged to be chosen by Yale as a trusted partner CRO to help the entrepreneur scientists’ transition their research towards commercialization” said Prabal Banerjee, PhD, Director of Business Development for GD3. "The ability to provide integrated services to projects as they transition from discovery to development is always reassuring for partners like Yale.”
This partner arrangement was made possible by a grant from the Blavatnik Family Foundation. This multi-year grant supports the Blavatnik Fund for Innovation at Yale, which was designed to bridge the gap between life science research and business and support faculty in the commercialization of applied research and technology. The fund’s recent commitment of $25 million has created new opportunities for emerging ventures and biotech companies.
Genesis Biotechnology Group acquires Comparative Biosciences, Inc. (CBI) to add GLP Toxicology and Safety Pharmacology to its portfolio of Preclinical Services
Posted August, 2019
Genesis Drug Discovery & Development (GD3), a member of Genesis Biotechnology Group (GBG) announced today that it has acquired Comparative Biosciences, Inc. (CBI), a Contract Research Organization (CRO) located in Sunnyvale, California. CBI is specialized in GLP (Good Laboratory Practice) Toxicology and Safety Pharmacology projects for IND-enabling research studies. This portfolio addition will enable GD3 to expand its pre-clinical services to GLP based studies by (1) offering integrated, single-point-of-contact services throughout the project lifetime, (2) streamlining all phases of the discovery cycle and (3) enabling new discoveries to progress rapidly from project inception through pre-clinical development. CBI’s skilled team of scientists, will work synergistically with GD3’s existing services around preclinical drug discovery.
“This acquisition is another strategic milestone for GBG in support of our vision to build a world class fully integrated CRO,” says Dr. Eli Mordechai, CEO of GBG. “Adding CBI is another way to differentiate our capabilities in the preclinical space. The acquisition of CBI significantly enhances our capabilities for providing IND enabling studies in Toxicology and Safety Pharmacology to better serve our industry partners.”
“M&A transactions in several sectors are paused or abandoned due to pandemic, but the CRO sector is less affected” says Dr. Ben Bandaru, Director of Corporate Development at GBG. We are seeing a temporary uptake in our service business as Pandemic related restrictions have forced Pharma and Biotech companies to increase outsourcing. However, timing of when things return to normalcy is still uncertain, so providing forward guidance continues to be a challenge in the short term.”
“Selling a business that we have built in a span of 20 years is not an easy decision but we are excited to be a part of GD3’s integrated portfolio of contract research services, as it would benefit our clients tremendously” says Dr. Carol Meschter, CEO of CBI. This acquisition allows us the opportunity to provide a more complete package of services to our clients and creates opportunity for our team to grow and evolve with a boarder platform.
Genesis Drug Discovery & Development (GD3) Announces Appointment of Anthony Rohr, as Chief Executive Officer of PharmOptima.
Posted August, 2019
PharmOptima, a member of Genesis Drug Discovery & Development (GD3), the contract research organization (CRO) arm of Genesis Biotechnology Group® (GBG), has announced the appointment of Anthony Rohr as its new Chief Executive Officer. In this capacity, as an expansion of his current role in Business Development, he will provide leadership, oversight, and coordination for the development and management of new preclinical drug discovery platforms.
Anthony brings a wealth of experience in a senior leadership capacity from his previous role at MPI Research, Inc. He is an experienced strategist with deep industry knowledge and an understanding of how to build CRO business while leveraging operational scale across a dispersed footprint. He is a strong leader with a proven track record of developing diverse and high performing teams.
“I am excited to undertake this role as part of such a dynamic and knowledgeable PharmOptima team,” said Rohr. “With the addition of laboratory space and scientific staff on the horizon and our reputation as a quality and responsive CRO, PharmOptima is positioned to leverage our strengths and investment into a prosperous future. I am also thrilled to be a part of the Genesis Drug Discovery and Development leadership team. We continue to round out our preclinical services through organic growth and acquisitions in the pursuit of creating the best fullservice preclinical organization in the market.”
Anthony has distinguished himself with over 15 years of experience in the preclinical research and CRO industries. “We look forward to continuing to work closely with Anthony in his newly expanded role as an advisor and collaborative partner to pharmaceutical, sponsor, and academic organizations” said Dr. Eli Mordechai, CEO of Genesis Biotechnology Group.
Genesis Biotechnology Group Acquires New England Discovery Partners
Posted November, 2019
Genesis Drug Discovery & Development (GD3), a member of Genesis Biotechnology Group, has acquired New England Discovery Partners (NEDP), a Contract Research Organization (CRO) specializing in synthetic and medicinal chemistry. This chemistry service portfolio addition will enable the GD3 family of companies to expand its pre-clinical drug research and discovery services to partners in pharma and academia by (1) offering integrated, single point-of-contact services throughout the project lifetime, (2) streamlining all phases of the discovery cycle and (3) enabling new discoveries to move rapidly from project inception through preclinical development.
NEDP’s skilled team of chemists, with almost 250 years of combined pharma and CRO experience, will work synergistically with GD3’s existing services around uHTS, computational chemistry, and structural biology. http://www.genesisbiotechgroup.com/press/PR_GD3_NEDP.pdf
New England Discovery Partners Secures STTR Grant
Posted January, 2019
New England Discovery Partners team up with Yale School of Medicine to develop novel small molecule drugs that combat severe viral disease caused by mosquito-transmitted viruses. The drugs are designed to specifically target those human proteins that the viruses need to successfully establish infection. The drugs will have broad-spectrum activity against multiple medically important flaviviruses including West Nile virus, Dengue virus and Zika virus. This work stems from a multidisciplinary collaboration with expertise in viral genetics, drug discovery, and medicinal chemistry and a team composed of Dr. Joseph Contessa of Yale School of Medicine, Dr. Jan Carette of Stanford, and Dr. Michael Van Zandt from Branford’s New England Discovery Partners (https://nedp.com).
The group has been awarded a small business technology transfer (STTR) grant of $600,000 from the National Institutes of Health in order to advance this approach for generating new medicines to treat infectious diseases.
Patent Application Awarded for Resolvin-Based Therapeutic Agents
Posted September, 2018
The U.S. Patent and Trademark Office has granted US Patent No. 10,130,719 which provids composition of matter patent protection for TP-317, a novel derivative of Resolvin E1 (RvE1) for treatment of inflammatory bowel disease (IBD).
Resolvins, are endogenous lipid autacoids that play a critical role in regulating inflammation resolution and tissue repair throughout the body. By delivering therapeutic doses of Resolvins to activate these intrinsic pathways, the drug candidate offers a new approach for treating inflammatory disease by activating intrinsic inflammation resolution pathways without compromising immune function.
This work has been completed as part of a sponsored research collaboration with Thetis Pharmaceuticals.
RNA-Based Therapeutics: Discovery of Novel Small Molecule Inhibitors of the Group II Intron
Posted June, 2018
Medicinal chemists at New England Discovery Partners have co-authored a ground-breaking paper on novel RNA-based small molecule antimicrobials. While working in collaboration with Professor Anna Marie Pyle at Yale University, a team of medicinal chemists at NEDP have discovered a novel series of group II intron inhibitors for treatment of fungal infections.
This work demonstrates that biologically important RNA molecules can be targeted with high specificity, potency and efficacy using the tools of medicinal chemistry and microbiology. This promising new class of antimicrobials, which targets a fungal-specific RNA processing mechanism, is likely to be far less toxic to humans than existing types of therapy. Although work still needs to be done, this first-generation series of inhibitors already have potencies comparable to amphotericin B, the current standard of care.
This important work, which was published in Nature Chemical Biology (Fedorova et al, (2018) 14, 1073-1078), has been the subject of commentary in Chemical & Engineering News, Nature Reviews Drug Discovery, Genetic Engineering and Biotechnology News and other media outlets (see links below).
This work was generously funded through a Small Business Innovative Research (SBIR) grant from the NIH, National Institute of Allergy and Infectious Diseases (Grant 1R43AI115951-01A1).
Published Paper: Small molecules that target group II introns are potent antifungal agents
Olga Fedorova, G. Erik Jagdmann, Rebecca L. Adams, Lin Yuan, Michael C. Van Zandt and Anna Marie Pyle
Nature Chemical Biology 2018 Vol 14, pages 1073–1078.
Palacino, “The splice is right” J. News and Views in Nature Chem. Biol. (2018).
Nature Reviews Drug Discovery, “Small molecules targeting a tertiary RNA structure fight fungi”
Genetic Engineering and Biotechnology News: “Fungal RNAs targeted”
Chemical & Engineering News: “Targeting RNA’s tertiary structure”
Thetis Pharmaceuticals Extends Research Collaboration with NEDP for 6th Straight Year
Posted May, 2018
Thetis Pharmaceuticals, a privately-held biopharmaceutical company developing novel small molecule therapies based on a class of potent pro-resolving lipid mediators known as Resolvins, extended it collaboration with New England Discovery Partners for the sixth straight year.
Frank Sciavolino, Ph.D., co-founder, president and chief scientific officer of Thetis commented, “New England Discovery Partners has played a critical role in the success of our company. Michael Van Zandt and the team have done a magnificent job developing new innovative syntheses that will enable cost-effective, large-scale production of these highly complex molecules.”
Resolvins, part of the superfamily of Specialized Pro-Resolving Lipid Mediators (SPMs), are endogenous lipid autacoids that play a critical role in regulating inflammation resolution and tissue repair throughout the body. By delivering therapeutic doses of Resolvins to activate these intrinsic pathways, the drug candidate offers a new approach to treating inflammatory disease by activating intrinsic inflammation resolution pathways without compromising immune function.